| 8:00 PM | Fri, September 25th at 8:00 PM EDT | Northwestern Wildcats 0 | @ | 0 Indiana Hoosiers | NU 0% · IU 100% | Memorial Stadium (Bloomington, IN) | FOX |
| 10:30 PM | Fri, September 25th at 10:30 PM EDT | Clemson Tigers 0 | @ | 0 California Golden Bears | CLEM 100% · CAL 0% | California Memorial Stadium | ESPN |
| 12:00 PM | Final | Texas Longhorns 20 | @ | 17 Tennessee Volunteers | — | Neyland Stadium | ABC |
| 12:00 PM | Final | Illinois Fighting Illini 19 | @ | 42 Ohio State Buckeyes | — | Ohio Stadium | FOX |
| 12:00 PM | Final | Sam Houston Bearkats 14 | @ | 49 Texas Tech Red Raiders | — | Galaxy Stadium | TNT |
| 12:00 PM | Final | Wake Forest Demon Deacons 30 | @ | 27 Louisville Cardinals | — | L&N Federal Credit Union Stadium | ESPN, Disney+ |
| 12:00 PM | Final | Colorado Buffaloes 13 | @ | 23 Baylor Bears | — | McLane Stadium | ESPN2 |
| 12:00 PM | Final | Bucknell Bison 0 | @ | 59 Pittsburgh Panthers | — | Acrisure Stadium | ACCNX |
| 12:00 PM | Final | Virginia Tech Hokies 21 | @ | 14 Boston College Eagles | — | Alumni Stadium (Chestnut Hill, MA) | ACC Network |
| 12:00 PM | Final | San Diego State Aztecs 16 | @ | 41 Toledo Rockets | — | Glass Bowl | CBSSN |
| 12:00 PM | Final | Colorado State Rams 45 | @ | 59 UTSA Roadrunners | — | Alamodome | ESPNU |
| 12:00 PM | Final | UNLV Rebels 38 | @ | 10 Akron Zips | — | InfoCision Stadium | ESPN+ |
| 12:00 PM | Final | Ball State Cardinals 13 | @ | 26 Kent State Golden Flashes | — | Zoeller Field at Dix Stadium | ESPN+ |
| 12:45 PM | Final | South Alabama Jaguars 21 | @ | 45 Kentucky Wildcats | — | Kroger Field | SEC Network |
| 1:00 PM | Final | Lindenwood Lions 3 | @ | 29 Eastern Michigan Eagles | — | Rynearson Stadium | ESPN+ |
| 1:30 PM | Final | UCLA Bruins 54 | @ | 3 Maryland Terrapins | — | SECU Stadium | BTN |
| 2:00 PM | Final | Notre Dame Fighting Irish 49 | @ | 10 Purdue Boilermakers | — | Ross-Ade Stadium | Peacock |
| 2:00 PM | Final | Northern Illinois Huskies 14 | @ | 35 Georgia State Panthers | — | Center Parc Stadium | ESPN+ |
| 3:00 PM | 2:28 - 3rd Quarter · 2:28 | Central Arkansas Bears 7 | @ | 31 Florida State Seminoles | — | Doak Campbell Stadium | ACC Network |
| 3:00 PM | 3:45 - 3rd Quarter · 3:45 | Hawai'i Rainbow Warriors 3 | @ | 13 Wyoming Cowboys | — | War Memorial Stadium | CW |
| 3:30 PM | Halftime · 0:00 | Oklahoma Sooners 0 | @ | 28 Georgia Bulldogs | — | Sanford Stadium | ESPN, Disney+ |
| 3:30 PM | 1:11 - 2nd Quarter · 1:11 | Ole Miss Rebels 6 | @ | 17 Florida Gators | — | Ben Hill Griffin Stadium | ABC |
| 3:30 PM | Halftime · 0:00 | Utah Utes 24 | @ | 3 Iowa State Cyclones | — | Jack Trice Stadium | FOX |
| 3:30 PM | Halftime · 0:00 | Iowa Hawkeyes 7 | @ | 10 Michigan Wolverines | — | Michigan Stadium | CBS |
| 3:30 PM | Halftime · 0:00 | TCU Horned Frogs 10 | @ | 14 UCF Knights | — | Acrisure Bounce House | FS1 |
| 3:30 PM | Halftime · 0:00 | William & Mary Tribe 7 | @ | 38 Duke Blue Devils | — | Wallace Wade Stadium | ACCNX |
| 3:30 PM | 10:51 - 3rd Quarter · 10:51 | Boise State Broncos 15 | @ | 0 Western Michigan Broncos | — | Waldo Stadium | ESPN2 |
| 3:30 PM | 12:58 - 3rd Quarter · 12:58 | UConn Huskies 14 | @ | 14 Miami (OH) RedHawks | — | Yager Stadium | ESPN+ |
| 3:30 PM | End of 2nd Quarter · 0:00 | New Mexico Lobos 14 | @ | 3 New Mexico State Aggies | — | Aggie Memorial Stadium | CBSSN |
| 3:30 PM | Halftime · 0:00 | Robert Morris Colonials 14 | @ | 14 Buffalo Bulls | — | Broadview Stadium | ESPN+ |
| 3:30 PM | 10:14 - 3rd Quarter · 10:14 | Stonehill Skyhawks 7 | @ | 14 Ohio Bobcats | — | Peden Stadium | ESPN+ |
| 3:30 PM | Halftime · 0:00 | Gardner-Webb Runnin' Bulldogs 21 | @ | 27 Marshall Thundering Herd | — | Joan C. Edwards Stadium | ESPN+ |
| 4:00 PM | 2:44 - 2nd Quarter · 2:44 | Houston Cougars 21 | @ | 14 Georgia Southern Eagles | — | Allen E. Paulson Stadium | ESPNU |
| 4:00 PM | 4:07 - 2nd Quarter · 4:07 | North Carolina Central Eagles 3 | @ | 28 East Carolina Pirates | — | Dowdy-Ficklen Stadium | ESPN+ |
| 4:15 PM | 7:15 - 2nd Quarter · 7:15 | Vanderbilt Commodores 3 | @ | 14 Auburn Tigers | — | Jordan-Hare Stadium | SEC Network |
| 5:00 PM | 9:13 - 1st Quarter · 9:13 | Wisconsin Badgers 0 | @ | 0 Penn State Nittany Lions | — | Beaver Stadium | Peacock |
| 5:00 PM | 11:14 - 1st Quarter · 11:14 | Nebraska Cornhuskers 0 | @ | 0 Michigan State Spartans | — | Spartan Stadium | BTN |
| 5:00 PM | 6:09 - 1st Quarter · 6:09 | South Florida Bulls 0 | @ | 3 Bowling Green Falcons | — | Doyt L. Perry Stadium | ESPN+ |
| 6:00 PM | Sat, September 26th at 6:00 PM EDT | Delaware Blue Hens 0 | @ | 0 Virginia Cavaliers | — | Scott Stadium | ACC Network |
| 6:00 PM | Sat, September 26th at 6:00 PM EDT | Incarnate Word Cardinals 0 | @ | 0 Texas State Bobcats | — | UFCU Stadium | USA Net |
| 6:00 PM | Sat, September 26th at 6:00 PM EDT | Long Island University Sharks 0 | @ | 0 Florida International Panthers | — | Pitbull Stadium | ESPN+ |
| 6:00 PM | Sat, September 26th at 6:00 PM EDT | James Madison Dukes 0 | @ | 0 Old Dominion Monarchs | — | S.B. Ballard Stadium | ESPN+ |
| 6:30 PM | Sat, September 26th at 6:30 PM EDT | Central Michigan Chippewas 0 | @ | 0 Miami Hurricanes | — | Hard Rock Stadium | CW |
| 6:30 PM | Sat, September 26th at 6:30 PM EDT | Louisiana Ragin' Cajuns 0 | @ | 0 Charlotte 49ers | — | Jerry Richardson Stadium | ESPN+ |
| 7:00 PM | Sat, September 26th at 7:00 PM EDT | South Carolina Gamecocks 0 | @ | 0 Alabama Crimson Tide | — | Bryant-Denny Stadium | ESPN |
| 7:00 PM | Sat, September 26th at 7:00 PM EDT | Kansas State Wildcats 0 | @ | 0 Cincinnati Bearcats | — | Nippert Stadium | ESPN2 |
| 7:00 PM | Sat, September 26th at 7:00 PM EDT | Oklahoma State Cowboys 0 | @ | 0 West Virginia Mountaineers | — | Milan Puskar Stadium | FS1 |
| 7:00 PM | Sat, September 26th at 7:00 PM EDT | Southern Miss Golden Eagles 0 | @ | 0 Tulane Green Wave | — | Yulman Stadium | ESPN+ |
| 7:00 PM | Sat, September 26th at 7:00 PM EDT | Kennesaw State Owls 0 | @ | 0 Arkansas State Red Wolves | — | Centennial Bank Stadium | ESPN+ |
| 7:00 PM | Sat, September 26th at 7:00 PM EDT | Mercyhurst Lakers 0 | @ | 0 Western Kentucky Hilltoppers | — | Houchens Industries-L.T. Smith Stadium | ESPN+ |
| 7:00 PM | Sat, September 26th at 7:00 PM EDT | Middle Tennessee Blue Raiders 0 | @ | 0 Jacksonville State Gamecocks | — | AmFirst Stadium | ESPN+ |
| 7:30 PM | Sat, September 26th at 7:30 PM EDT | Texas A&M Aggies 0 | @ | 0 LSU Tigers | — | Tiger Stadium (LA) | ABC |
| 7:30 PM | Sat, September 26th at 7:30 PM EDT | Oregon Ducks 0 | @ | 0 USC Trojans | — | Los Angeles Memorial Coliseum | NBC |
| 7:30 PM | Sat, September 26th at 7:30 PM EDT | Arizona Wildcats 0 | @ | 0 Washington State Cougars | — | Martin Stadium | CBS |
| 7:30 PM | Sat, September 26th at 7:30 PM EDT | Troy Trojans 0 | @ | 0 Utah State Aggies | — | Maverik Stadium | CBSSN |
| 7:30 PM | Sat, September 26th at 7:30 PM EDT | Houston Christian Huskies 0 | @ | 0 North Texas Mean Green | — | DATCU Stadium | ESPN+ |
| 7:30 PM | Sat, September 26th at 7:30 PM EDT | App State Mountaineers 0 | @ | 0 NC State Wolfpack | — | Carter-Finley Stadium | ESPNU |
| 7:45 PM | Sat, September 26th at 7:45 PM EDT | Missouri Tigers 0 | @ | 0 Mississippi State Bulldogs | — | Davis Wade Stadium | SEC Network |
