| 1:40 PM | St. Louis Cardinals @ Cincinnati Reds | | | | | | — | — | ESPN picks |
| 6:05 PM | Baltimore Orioles @ Tampa Bay Rays | | TB -163 | 8 | AWY 135 HM -163 | | — | — | ESPN picks |
| 6:40 PM | Miami Marlins @ Philadelphia Phillies | | PHI -258 | 8 | AWY 208 HM -258 | | — | — | ESPN picks |
| 6:40 PM | St. Louis Cardinals @ Cincinnati Reds | | | | | | — | — | ESPN picks |
| 7:00 PM | Detroit Tigers @ Pittsburgh Pirates | | DET -123 | 8 | AWY -123 HM 102 | | — | — | ESPN picks |
| 7:10 PM | Arizona Diamondbacks @ Boston Red Sox | | BOS -156 | 9 | AWY 129 HM -156 | | — | — | ESPN picks |
| 7:10 PM | San Diego Padres @ New York Mets | | NYM -120 | 8 | AWY 100 HM -120 | | — | — | ESPN picks |
| 7:40 PM | Athletics @ Kansas City Royals | | KC -198 | 9 | AWY 163 HM -198 | | — | — | ESPN picks |
| 7:40 PM | Atlanta Braves @ Minnesota Twins | | ATL -131 | 9 | AWY -131 HM 109 | | — | — | ESPN picks |
